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Sodium Hyaluronate BP Ph Eur Supplier, Manufacturer's Representative, CAS Number 9067-32-7
FInOrIC, etymologically derived from our business line of Fine Inorganic, Organic and Industrial Chemicals, offers chemicals for Oil & Gas Exploration, Hydraulic Fracturing, Production, Stimulation, Coiled Tubing, Food & Feed Ingredients, Mineral Fortifiers and Pharmaceutical Excipients, in 55 countries across 5 continents. Backed by company owned & operated full-fledged chemical manufacturing facilities in Pleasanton, Midland & Houston, Texas with associated manufacturing sites in India, UAE and China we are a truly multi-national chemical manufacturer and distributor.
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For MSDS Sheet Click MSDS SDS of Sodium Hyaluronate Suppliers
CAS Number 9067-32-7 BP Ph Eur Suppliers
Sodium Hyaluronate BP Grade
Ph Eur monograph
(C14H20NNaO11)n --- CAS Number 9067-32-7
Action and use: High viscosity mucopolysaccharide.
Sodium salt of hyaluronic acid, a glycosaminoglycan consisting of D-glucuronic acid and Nacetyl- D-glucosamine disaccharide units.
Content: 95.0 per cent to 105.0 per cent (dried substance).
Intrinsic viscosity: 90 per cent to 120 per cent of the value stated on the label.
It is extracted from cocks' combs or obtained by fermentation from Streptococci, Lancefield Groups A and C. When produced by fermentation of gram-positive bacteria, the process must be shown to reduce or eliminate pyrogenic or inflammatory components of the cell wall.
Appearance: White or almost white, very hygroscopic powder or fibrous aggregate.
Solubility: Sparingly soluble or soluble in water, practically insoluble in acetone and in anhydrous ethanol.
A. Infrared absorption spectrophotometry. ComparisonıPh. Eur. reference spectrum of sodium hyaluronate.
B. It gives reaction of sodium.
Solution S: Weigh a quantity of the substance to be examined equivalent to 0.10 g of the dried substance and add 30.0 ml of a 9 g/l solution of sodium chloride. Mix gently on a shaker until dissolved (about 12 h).
Appearance of solution: Solution S is clear and its absorbance at 600 nm is not greater than 0.01.
pH: 5.0 to 8.5.
Dissolve the substance to be examined in carbon dioxide-free water to obtain a solution containing a quantity equivalent to 5 mg of the dried substance per millilitre.
Intrinsic viscosity: To pass the test.
Sulphated glycosaminoglycans: Maximum 1 per cent, if the product is extracted from cocks' combs.
Nucleic acids: The absorbance of solution S at 260 nm is maximum 0.5.
Protein: Maximum 0.3 per cent; maximum 0.1 per cent, if intended for use in the manufacture of parenteral preparations.
Chlorides: Maximum 0.5 per cent.
Iron: Maximum 80.0 ppm.
Heavy metals: Maximum 20 ppm; maximum 10 ppm if intended for use in the manufacture of parenteral preparations.
Loss on drying: Maximum 20.0 per cent, determined on 0.500 g by drying at 100-110C over diphosphorus pentoxide for 6 h.
Microbial contamination: Total viable aerobic count not more than 100 micro-organisms per gram. Use 1 g of the substance to be examined.
Bacterial endotoxins: Less than 0.5 IU/mg, if intended for use in the manufacture of parenteral preparations without a further appropriate procedure for the removal of bacterial endotoxins; less than 0.05 IU/mg, if intended for use in the manufacture of intra-ocular preparations or intra-articular preparations without a further appropriate procedure for the removal of bacterial endotoxins.
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16 March, 2022